CD4 antibody (PE)

Catalog No. ABIN1819613

The Rat Monoclonal anti-CD4 antibody has been validated for FACS, IHC and IHC (fro). It is suitable to detect CD4 in samples from Dog.

Quick Overview for CD4 antibody (PE) (ABIN1819613)

Target: CD4

Reactivity: Dog

Host: Rat

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to PE

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: YKIX302-9

Product Details anti-CD4 Antibody (PE)

Specificity: Is a monoclonal antibody specific for the canine CD4 cell surface antigen. Clone YKIX302.9 was clustered at the first Canine Leukocyte Antigen Workshop (CLAW) [] along with clone CA13.1E4. Has been demonstrated to partially deplete circulating T lymphocytes when administered in vivo, but alone was not sufficient to prolong allograft survival in a canine transplant model. Uniquely amongst mammals, canine CD4 is expressed by neutrophils as well as by lymphocytes subsets. Forms part of a panel of anti canine monoclonal antibodies used extensively in the evaluation of leukemic status in dogs.

Purification: Protein G purified

Immunogen: Canine Concanavalin A activated T-cell blasts.

Type of Immunogen: Cells

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (1:1 - 1:10), IHC, IHC-Fr

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Dog

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Protect from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: Name/Gene ID: CD4

Synonyms: CD4, CD4 antigen, CD4 receptor, CD4mut, CD4 antigen (p55), CD4 Molecule

Gene ID: 920

UniProt: P01730

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events