TREM2 antibody
Quick Overview for TREM2 antibody (ABIN6796398)
Target
See all TREM2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Specificity
- Recognizes Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 with clone 78.18 enhances multinucleated osteoclast formation in vitro. Clone 78.18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts.
-
Purification
- Protein G purified
-
Immunogen
-
Mouse TREM-2 Fc fusion protein.
Type of Immunogen: Fusion protein -
Isotype
- IgG1
-
-
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 1-228) antibody
TREM2 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 1-100) antibodyTREM2 Reactivity: Mouse, Human, Rat, Pig WB, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 22-48), (N-Term) antibodyTREM2 Reactivity: Mouse WB, IHC (p) Host: Rabbit Polyclonal RB38661 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 1-227) antibodyTREM2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (Internal Region) antibodyVerified TREM2 Reactivity: Mouse ELISA, IF Host: Goat Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 42-56), (Extracellular) antibodyTREM2 Reactivity: Mouse WB, IHC, FACS, LCI Host: Rabbit Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-174) antibodyTREM2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) antibody (PE)TREM2 Reactivity: Mouse FACS Host: Rat Monoclonal 78-18 PE
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-161) antibodyTREM2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2B5 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 42-56), (Extracellular) antibody (PE)TREM2 Reactivity: Mouse FACS, LCI Host: Rabbit Polyclonal PE
-
-
Application Notes
- Approved: Flo (1:25 - 1:200)
-
Comment
-
Target Species of Antibody: Mouse
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- PBS, 0.09 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freezing and thawing.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
-
-
- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
-
Alternative Name
- TREM2 / TREM-2
-
Background
-
Name/Gene ID: TREM2
Synonyms: TREM2, Trem2b, TREM-2, Trem2a, Trem2c -
Gene ID
- 54209
-
UniProt
- Q9NZC2
Target
-
