MAP3K7 antibody (Gln600)

Catalog No. ABIN1820323

This Rabbit Monoclonal antibody specifically detects MAP3K7 in WB and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MAP3K7 antibody (Gln600) (ABIN1820323)

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MAP3K7 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 5BH5

Product Details anti-MAP3K7 Antibody

Binding Specificity: Gln600

Specificity: Endogenous levels of total TAK1. Species Crossreactivity: mouse, rat.

Purification: Purified

Immunogen: Synthetic peptide corresponding to residues surrounding Gln600 of human TAK1.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IP (1:50), WB

Usage: Western Blot: 1:1000 Incubate membrane with diluted antibody in 5 % w/v BSA, 1X TBS, 0.1 % Tween-20 at 4 °C with gentle shaking, overnight.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 100 μg/mL BSA, less than 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for MAP3K7

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Alternative Name: MAP3K7 / TAK1

Background: Name/Gene ID: MAP3K7
Subfamily: MLK(MAP3K)
Family: Protein Kinase

Synonyms: MAP3K7, MEKK7, TGF-beta activated kinase 1, TGF1a, TAK1, TGF-beta-activated kinase 1

Gene ID: 6885

UniProt: O43318

Pathways: NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway