Topoisomerase II alpha antibody (AA 1174-1531)

Catalog No. ABIN1823137

This Mouse Monoclonal antibody specifically detects Topoisomerase II alpha in WB. It exhibits reactivity toward Human.

Quick Overview for Topoisomerase II alpha antibody (AA 1174-1531) (ABIN1823137)

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Topoisomerase II alpha antibody is un-conjugated

Application: Western Blotting (WB)

Clone: TS106

Product Details anti-Topoisomerase II alpha Antibody

Binding Specificity: AA 1174-1531

Specificity: Human TOP2A. No cross-reactivity with recombinant TOP2B from human or mouse.

Purification: Affinity purified

Immunogen: Recombinant corresponding to aa1174-1531 from human TOP2A expressed in E. Coli (P11388).

Type of Immunogen: Recombinant protein

Isotype: IgG2a

Application Details

Application Notes: Approved: WB (0.5 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile PBS to 0.5 mg/mL.

Concentration: Lot specific

Buffer: Lyophilized from PBS, trehalose

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.

Target Details for Topoisomerase II alpha

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Alternative Name: TOP2A / Topoisomerase II alpha

Background: Name/Gene ID: TOP2A
Family: Topoisomerase

Synonyms: TOP2A, DNA topoisomerase II, 170 kD, TOP2, DNA gyrase, DNA topoisomerase 2-alpha, TP2A

Gene ID: 7153

UniProt: P11388

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases