SLA Class I antibody

Catalog No. ABIN1834930

This Mouse Monoclonal antibody specifically detects SLA Class I in FACS and IP. It exhibits reactivity toward Human and Pig.

Quick Overview for SLA Class I antibody (ABIN1834930)

Target: SLA Class I

Reactivity: Human, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: JM1E3

Product Details

Specificity: The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. Clone JM1E3 recognizes a monomorphic epitope expressed by porcine MHC class I molecules (SLA - 1). SLA - 1 is expressed by all nucleated porcine cells, but not on erythrocytes. Has also been shown to cross-react with human MHC Class I, including HLA-E. Is reported to block the interaction of MHC Class I antigens with inhibitory NK cell receptors. Removal of sodium azide is recommended prior to use in functional assays -.

Purification: Protein G purified

Immunogen: Porcine peripheral blood mononuclear cells.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Pig

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details

Target: SLA Class I