TIAM1 antibody (N-Term)

Catalog No. ABIN1841841

This anti-TIAM1 antibody is a Rabbit Polyclonal antibody detecting TIAM1 in WB and IHC. Suitable for Human.

Quick Overview for TIAM1 antibody (N-Term) (ABIN1841841)

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIAM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TIAM1 Antibody

Binding Specificity: N-Term

Purpose: Rabbit antibody to TIAM 1

Specificity: Specific for TIAM1.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from n-terminal region of human T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 TIAM1) conjugated to an immunogenic carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for TIAM1

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Alternative Name: TIAM 1

Background: FUNCTION: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1 CDC42 and to a lesser extent RHOA. SUBUNIT: Interacts with BAIAP2. TISSUE SPECIFICITY: Found in virtually all analyzed tumor cell lines including B- and T-lymphomas neuroblastomas melanomas and carcinomas.

UniProt: Q13009