TIAM1 antibody (AA 1392-1591)

Catalog No. ABIN6149146

This Rabbit Polyclonal antibody specifically detects TIAM1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for TIAM1 antibody (AA 1392-1591) (ABIN6149146)

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIAM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TIAM1 Antibody

Binding Specificity: AA 1392-1591

Sequence: SILRDKHRRQ LLKTESLPSS QQYVPFGGKR LCALKGARPA MSRAVSAPSK SLGRRRRRLA RNRFTIDSDA VSASSPEKES QQPPGGGDTD RWVEEQFDLA QYEEQDDIKE TDILSDDDEF CESVKGASVD RDLQERLQAT SISQRERGRK TLDSHASRMA QLKKQAALSG INGGLESASE EVIWVRREDF APSRKLNTEI

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1392-1591 of human TIAM1 (NP_003244.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TIAM1

Target: TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

Alternative Name: TIAM1

Background: Guanyl-nucleotide exchange factor that activates RHO-like proteins and connects extracellular signals to cytoskeletal activities. Activates RAC1, CDC42, and to a lesser extent RHOA and their downstream signaling to regulate processes like cell adhesion and cell migration.,TIAM1,Signal Transduction,G protein signaling,Cell Biology & Developmental Biology,Cytoskeleton,Actins,TIAM1

Molecular Weight: 170 kDa/177 kDa

Gene ID: 7074

UniProt: Q13009