alpha Fetoprotein antibody

Catalog No. ABIN1842706

This Mouse Monoclonal antibody specifically detects alpha Fetoprotein in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for alpha Fetoprotein antibody (ABIN1842706)

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This alpha Fetoprotein antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-alpha Fetoprotein Antibody

Purification: Purified by Protein G affinity chromatography

Immunogen: Purified recombinant fragment of human AFP expressed in E. coli.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol and 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Alternative Name: AFP

Background: AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life.Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma.However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology.The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4.Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin.The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Molecular Weight: 69 kDa

Gene ID: 174, 11576

Pathways: C21-Steroid Hormone Metabolic Process