BMPR1A antibody (AA 179-378)

Catalog No. ABIN1845272

The Mouse Monoclonal anti-BMPR1A antibody is suitable to detect BMPR1A in samples from Human. It has been validated for WB, ELISA, IHC and FACS.

Quick Overview for BMPR1A antibody (AA 179-378) (ABIN1845272)

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BMPR1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-BMPR1A Antibody

Binding Specificity: AA 179-378

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human BMPR1A (AA: 179-378) expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for BMPR1A

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Alternative Name: BMPR1A

Background: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2.These receptors are also closely related to the activin receptors, ACVR1 and ACVR2.The ligands of these receptors are members of the TGF-beta superfamily.TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD.Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Molecular Weight: 60 kDa

Gene ID: 657

UniProt: P36894

Pathways: Stem Cell Maintenance