CEBPA antibody
Quick Overview for CEBPA antibody (ABIN1845796)
Target
See all CEBPA AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Purification
- Purified antibody
-
Immunogen
- Purified recombinant fragment of human CEBPA expressed in E. Coli.
-
Isotype
- IgG1
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1.0 mg/mL
-
Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
-
-
- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
-
Alternative Name
- CEBPA
-
Background
- The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP beta and CEBP gamma . The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
-
Molecular Weight
- 42 kDa
-
Gene ID
- 1050
-
UniProt
- P49715
-
Pathways
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Target
-