The Mouse Monoclonal anti-CEBPA antibody (ABIN1845802) specifically detects CEBPA in WB, ELISA, IHC, FACS and IF/ICC.
The antibody is reactive with Human, Rat and Mouse samples.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Target
CEBPA
(CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
Alternative Name
CEBPA
Background
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers.It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma.The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis.Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.