RING1
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
2A6
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
1.0 mg/mL
Buffer
PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Target
RING1
(Ring Finger Protein 1 (RING1))
Alternative Name
Ring1
Background
This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain.The gene product can bind DNA and can act as a transcriptional repressor.It is associated with the multimeric polycomb group protein complex.The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains.It interacts with the CBX4 protein via its glycine-rich C-terminal domain.The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.