CD59 antibody (AA 31-111)

Catalog No. ABIN1845905

The Mouse Monoclonal anti-CD59 antibody has been validated for WB, FACS, IHC, ELISA and IF/ICC. It is suitable to detect CD59 in samples from Human.

Quick Overview for CD59 antibody (AA 31-111) (ABIN1845905)

Target: CD59

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD59 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-CD59 Antibody

Binding Specificity: AA 31-111

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD59 (AA: 31-111) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for CD59

Target: CD59

Alternative Name: CD59

Background: This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation.

Molecular Weight: 14.2 kDa

Gene ID: 966

UniProt: P13987

Pathways: Complement System