RUNX3 antibody (AA 186-252)

Catalog No. ABIN1846067

The Mouse Monoclonal anti-RUNX3 antibody is suitable to detect RUNX3 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC, FACS and IF/ICC.

Quick Overview for RUNX3 antibody (AA 186-252) (ABIN1846067)

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This RUNX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-RUNX3 Antibody

Binding Specificity: AA 186-252

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. coli.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Alternative Name: RUNX3

Background: This gene encodes a member of the runt domain-containing family of transcription factors.A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription.It also interacts with other transcription factors.It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer.Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 44.4 kDa

Gene ID: 864