TRF1 antibody (C-Term)

Catalog No. ABIN184696

This Goat Polyclonal antibody specifically detects TRF1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for TRF1 antibody (C-Term) (ABIN184696)

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-TRF1 Antibody

Binding Specificity: C-Term

Purpose: TERF1 / PIN2

Sequence: TMKKLKLISS DSED

Specificity: This antibody is expected to recognise isoform 1 (NP_059523.2) and isoform 2 (NP_003209.2).

Cross-Reactivity: Cow, Human, Pig

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: C-TMKKLKLISSDSED

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 60-65 kDa and 45 kDa bands seen in HeLa lysate. Recommended for use at 1-3 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:8000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for TRF1

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Alternative Name: TERF1

Background: TERF1, PIN2, TRF, TRF1, TRBF1, hTRF1-AS, telomeric repeat binding factor (NIMA-interacting) 1, Telomeric repeat binding factor 1, telomeric repeat binding protein 1, FLJ41416, t-TRF1

Gene ID: 7013

NCBI Accession: NP_003209, NP_059523

Pathways: Cell Division Cycle, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity