MCL-1 antibody (C-Term)

Catalog No. ABIN185242

This Goat Polyclonal antibody specifically detects MCL-1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for MCL-1 antibody (C-Term) (ABIN185242)

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This MCL-1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-MCL-1 Antibody

Binding Specificity: C-Term

Purpose: MCL1

Sequence: AGVGAGLAYL IR

Specificity: This antibody is expected to recognise reported isoform 1 (NP_068779.1) and isoform 3 (NP_001184249.1).

Cross-Reactivity: Cow, Dog, Human, Mouse, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-AGVGAGLAYLIR, from the C Terminus of the protein sequence according to NP_068779.1, NP_001184249.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 35 kDa band observed in lysates of Human Lung (calculated MW of 37.3 kDa according to NP_068779.1). Recommended concentration: 1-3 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Alternative Name: MCL1

Background: MCL1, TM, EAT, MCL1L, MCL1S, MGC1839, MGC104264, myeloid cell leukemia sequence 1 (BCL2-related), induced myeloid leukemia cell differentiation protein Mcl-1, myeloid cell leukemia sequence 1, myeloid cell leukemia sequence 1, isoform 1, BCL2L3, Mcl-1

Gene ID: 4170, 17210

NCBI Accession: NP_068779, NP_001184249

Pathways: MAPK Signaling