Retinoid X Receptor beta antibody (AA 70-83)

Catalog No. ABIN185296

This Goat Polyclonal antibody specifically detects Retinoid X Receptor beta in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Retinoid X Receptor beta antibody (AA 70-83) (ABIN185296)

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Retinoid X Receptor beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-Retinoid X Receptor beta Antibody

Binding Specificity: AA 70-83

Purpose: RXR beta

Sequence: CRDGMGDSGR DSRSP

Specificity: This antibody is expected to recognise an epitope corresponding to aa 70-83 of human RXR beta protein and does not cross-react with either RXR alpha or gamma.

Cross-Reactivity: Cow, Dog, Human, Mouse, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence CRDGMGDSGRDSRSP, from the internal region of the protein sequence according to NP_068811.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 55 kDa band observed in lysates of cell line A431 (calculated MW of 56.9 kDa according to NP_068811.1). In transfected HEK293 transiently expressing RXRB a band of approx. 60 kDa is observed. This band is not observed in the non-transf

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for Retinoid X Receptor beta

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Alternative Name: RXRB

Background: RXRB, NR2B2, DAUDI6, RCoR-1, MGC1831, H-2RIIBP, retinoid X receptor, beta, MHC class I promoter binding protein, DADB-100D22.1

Gene ID: 6257

NCBI Accession: NP_068811

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway