CREM antibody (C-Term)

Catalog No. ABIN185300

The Goat Polyclonal anti-CREM antibody has been validated for WB and ELISA. It is suitable to detect CREM in samples from Human.

Quick Overview for CREM antibody (C-Term) (ABIN185300)

Target: CREM (CAMP Responsive Element Modulator (CREM))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CREM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-CREM Antibody

Binding Specificity: C-Term

Purpose: CREM

Sequence: LETLKDICSP KTDY

Specificity: This antibody is expected to recognise the following protein isoforms of human CREM protein: a (NP_853549.1), e (NP_874387.1), f (NP_874388.1), k (NP_874393.1), l (NP_874394.1), m (NP_877570.1), n (NP_877571.1), o (NP_877572.1), p (NP_877573.1), q (NP_878

Cross-Reactivity: Cow, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence LETLKDICSPKTDY, from the C Terminus of the protein sequence according to NP_853549.1, NP_874387.1, NP_874388.1, NP_874393.1, NP_874394.1, NP_877570.1, NP_877571.1, NP_877572.1, NP_877573.1, NP_878270.1, NP_898883.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 35 kDa band observed in Human Heart lysates (calculated MW of 32.5 kDa according to NP_853549.1). Recommended concentration: 0.3-1 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for CREM

Target: CREM (CAMP Responsive Element Modulator (CREM))

Alternative Name: CREM

Background: CREM, ICER, MGC17881, MGC41893, MGC111110, hCREM-2, cAMP responsive element modulator, hCREM 2alpha-b protein, hCREM 2beta-a protein, inducible cAMP early repressor ICER, OTTHUMP00000019442, OTTHUMP00000019443, cAMP response element modulator, hCREM 2alph

Gene ID: 1390

NCBI Accession: NP_853549, NP_874387, NP_874388, NP_874393, NP_874394, NP_877570, NP_877571, NP_877572, NP_877573, NP_878270, NP_898883

Pathways: Retinoic Acid Receptor Signaling Pathway