CREM antibody (AA 1-100)

Catalog No. ABIN6139026

Product Details anti-CREM Antibody

Target: CREM (CAMP Responsive Element Modulator (CREM))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREM antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSKCARKKYI KTNPRQMTME TVESQHDGSI TASLTESKSA HVQTQTGQNS IPALAQVAAI AETDESAESE GVIDSHKRRE ILSRRPSYRK ILNELSSDVP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CREM (NP_853549.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CREM

Target: CREM (CAMP Responsive Element Modulator (CREM))

Alternative Name: CREM (CREM Products)

Synonyms: CREM antibody, ICER antibody, CREM-2 antibody, hCREM-2 antibody, ICERI antibody, Icer antibody, cAMP responsive element modulator antibody, CREM antibody, Crem antibody

Background: This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.,CREM,CREM-2,ICER,hCREM-2,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,CREM

Molecular Weight: 11-38 kDa

Gene ID: 1390

UniProt: Q03060

Pathways: Retinoic Acid Receptor Signaling Pathway