MC3R antibody (N-Term)

Catalog No. ABIN185386

This Goat Polyclonal antibody specifically detects MC3R in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for MC3R antibody (N-Term) (ABIN185386)

Target: MC3R (Melanocortin 3 Receptor (MC3R))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This MC3R antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-MC3R Antibody

Binding Specificity: N-Term

Purpose: Melanocortin 3 Receptor

Sequence: SIQKTYLEGD FV

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence SIQKTYLEGDFV-C, from the N Terminus of the protein sequence according to NP_063941.2.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 40 kDa band observed in Human Brain lysates (calculated MW of 40.1 kDa according to NP_063941.2). Recommended concentration: 1-3 μg/mL. Primary incubation was 1 hour.

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-MC3R antibody (ABIN185386)

Hawari, Ericsson, Kabeer, Chaussabel, Alsulaiti, Sharari, Maccalli, Khan, Hussain: "Understanding the Mechanism of Diabetes Mellitus in a LRBA-Deficient Patient." in: , Vol. 11, Issue 4, (2022) (PubMed).

Target Details for MC3R

Target: MC3R (Melanocortin 3 Receptor (MC3R))

Alternative Name: MC3R

Background: Melanocortin 3 receptor, MC3R, MC3, BMIQ9, MC3-R, OB20, OQTL, Obesity quantitative trait locus

Gene ID: 4159

NCBI Accession: NP_063941

Pathways: cAMP Metabolic Process