MC3R antibody (AA 280-360)

Catalog No. ABIN7229592

This Rabbit Polyclonal antibody specifically detects MC3R in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MC3R antibody (AA 280-360) (ABIN7229592)

Target: MC3R (Melanocortin 3 Receptor (MC3R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC3R antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MC3R Antibody

Binding Specificity: AA 280-360

Purpose: Rabbit Anti-MC3R Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MC3R protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MC3R protein at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MC3R

Target: MC3R (Melanocortin 3 Receptor (MC3R))

Alternative Name: MC3R

Background: Melanocortin receptor 3, MC3-RReceptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.

Molecular Weight: 35kD

Gene ID: 4159

UniProt: P41968

Pathways: cAMP Metabolic Process