beta 2 Adrenergic Receptor antibody (C-Term)

Catalog No. ABIN185478

This anti-beta 2 Adrenergic Receptor antibody is a Goat Polyclonal antibody detecting beta 2 Adrenergic Receptor in WB and ELISA. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for beta 2 Adrenergic Receptor antibody (C-Term) (ABIN185478)

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This beta 2 Adrenergic Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-beta 2 Adrenergic Receptor Antibody

Binding Specificity: C-Term

Purpose: ADRB2R / ADRB2

Sequence: HQGTVPSDNI DSQ

Cross-Reactivity: Cow, Dog, Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-HQGTVPSDNIDSQ, from the C Terminus of the protein sequence according to NP_000015.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 48 kDa band observed in lysates of cell lind HepG2 (calculated MW of 46.6 kDa according to NP_000015.1). Recommended concentration: 0.3-1 μg/mL. Primary incubation 1 hour at room temperature.

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-beta 2 Adrenergic Receptor antibody (ABIN185478)

Rekawiecki, Nowocin, Kotwica: "Relationship between concentrations of progesterone, oxytocin, noradrenaline, gene expression and protein level for their receptors in corpus luteum during estrous cycle in the cow." in: Prostaglandins & other lipid mediators, Vol. 92, Issue 1-4, pp. 13-8, (2010) (PubMed).

Target Details for beta 2 Adrenergic Receptor

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Alternative Name: ADRB2

Background: ADRB2, ADRB2R, adrenergic, beta-2-, receptor, surface , HGNC:286, ADRBR, B2AR, BAR, BETA2AR, beta-2 adrenergic receptor, beta-2 adrenoceptor, catecholamine receptor

Gene ID: 154

NCBI Accession: NP_000015

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation