FURIN antibody (AA 105-221)
Quick Overview for FURIN antibody (AA 105-221) (ABIN1857825)
Target
See all FURIN AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 105-221
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Purpose
- Monoclonal Antibody to Furin (FUR)
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Sequence
- MGHHHHHHSG SEF-TKRDVY QEPTDPKFPQ QWYLSGVTQR DLNVKAAWAQ GYTGHGIVVS ILDDGIEKNH PDLAGNYDPG ASFDVNDQDP DPQPRYTQMN DNRHGTRCAG EVAAVANNGV CGVGVAYNAR I
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Specificity
- The antibody is a mouse monoclonal antibody raised against FUR. It has been selected for its ability to recognize FUR in immunohistochemical staining and western blotting.
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Cross-Reactivity
- Mouse, Rat
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Purification
- Antigen-specific affinity chromatography followed by Protein A affinity chromatography
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Immunogen
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Recombinant FUR expressed in E.coli.USCN
The antibody is a mouse monoclonal antibody raised against FUR. -
Isotype
- IgG
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Application Notes
- Western blotting: 0.2-2 μg/mL,1:500-5000 Immunohistochemistry: 5-20 μg/mL,1:50-200 Immunocytochemistry: 5-20 μg/mL,1:50-200 Optimal working dilutions must be determined by end user.
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Comment
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The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Handling Advice
- Avoid repeated freeze/thaw cycles
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
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Alternative Name
- Furin
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Background
- PACE, PCSK3, SPC1, Paired Basic Amino Acid Cleaving Enzyme, Dibasic-processing enzyme
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Pathways
- Notch Signaling, Neurotrophin Signaling Pathway
Target
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