MVP antibody

Catalog No. ABIN187271

The Mouse Monoclonal anti-MVP antibody is suitable to detect MVP in samples from Human. It has been validated for FACS, IHC (p) and IHC (fro).

Quick Overview for MVP antibody (ABIN187271)

Target: MVP (Major Vault Protein (MVP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MVP antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: LRP-56

Product Details anti-MVP Antibody

Specificity: Monoclonal antibody recognizes the 110 kDa LRP protein. Reacts with an internal epitope of the LRP-protein, which is upregulated and strongly overexpressed in various human P-glycoprotein-negative MDR tumor cells. Species Reactivity: Human. Others not tested.

Immunogen: 110 kDa LRP-protein (p110).

Isotype: IgG2b

Application Details

Application Notes: LRP-56 has potential value for the detection of LRP-associated non-P-glycoprotein MDR in human tumor samples. Flow Cytometry: Use at least a 1:50 dilution after fixing cells in 10% (v/v) Lysing solution G (Becton-Dickinson) in H2O, followed by incubation with anti-mouse-FITC. Immunocytochemistry: Acetone-fixed cell preparations)- Use at least 1:20-50 dilution. Immunohistochemistry: (Acetone-fixed frozen sections or cytospin preparations)- Use at least a 1:20-50 dilution. (Formalin-fixed, paraffin-embedded tissues)- Use at a 1:20 dilution. The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.5 mL (>100 tests) containing approx. 100 µg IgG with protein stabilizer and 0.1% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for MVP

Target: MVP (Major Vault Protein (MVP))

Alternative Name: Major Vault Protein