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ABCA1 antibody
ABCA1
Reactivity: Human
WB, IP, IHC (fro), EIA
Host: Mouse
Monoclonal
AB1-G6
unconjugated
Product Details anti-ABCA1 Antibody
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Target
See all ABCA1 Antibodies
ABCA1
(ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
Reactivity
All reactivities for ABCA1 antibodies
Human
Host
All hosts for ABCA1 antibodies
Mouse
Clonality
All clonalities for ABCA1 antibodies
Monoclonal
Conjugate
All conjugates for ABCA1 antibodies
This ABCA1 antibody is un-conjugated
Application
All applications for ABCA1 antibodies
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
Specificity
Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder resulting from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI. Species Human. Other species not tested.
Immunogen
Peptide corresponding to amino acids 1800-2260.
Clone
AB1-G6
Isotype
IgG1
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Discover our top product ABCA1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Immunohistochemistry Western blot ELISA Immunoprecipitation The optimal dilution for a specific application should be determined by the researcher.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
100 µg of antibody at 1 mg/mL in PBS, pH 7.4, with 0.5% sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target Details for ABCA1
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Target
ABCA1
(ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
Alternative Name
ABCA1 (ABCA1 Products )
Synonyms
ABC-1 antibody, ABC1 antibody, CERP antibody, HDLDT1 antibody, TGD antibody, ABCA1 antibody, Abc1 antibody, ATP-binding cassette A1 antibody, Arabidopsis thaliana ATP-binding cassette A1 antibody, AtABCA1 antibody, im:7136239 antibody, sb:cb407 antibody, wu:fa07e06 antibody, zgc:171581 antibody, ATP binding cassette subfamily A member 1 antibody, ATP-binding cassette, sub-family A (ABC1), member 1 antibody, ATP-binding cassette A1 antibody, ATP-binding cassette, sub-family A (ABC1), member 1B antibody, ABCA1 antibody, Abca1 antibody, abca1 antibody, abca1b antibody
Pathways
Cellular Response to Molecule of Bacterial Origin , cAMP Metabolic Process , Regulation of Lipid Metabolism by PPARalpha , Lipid Metabolism
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