Caspase 7 antibody (AA 186-198)

Catalog No. ABIN187761

This anti-Caspase 7 antibody is a Rabbit Polyclonal antibody detecting Caspase 7 in WB. Suitable for Human.

Quick Overview for Caspase 7 antibody (AA 186-198) (ABIN187761)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Caspase 7 Antibody

Binding Specificity: AA 186-198

Specificity: Rabbit anti-human caspase-7 antibody reacts with the zymogen and with the 20-23 kDa subunit of caspase-7. Cells should be pretreated with 200 ng/ml of deoxyrubicin for one half hour. Species Reactivity: human, other species not tested.

Immunogen: A peptide representing amino acids 186-198 of human caspase-7.

Application Details

Application Notes: Western blot: use at 2-10 µg/ml. The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Buffer: 0

Storage: -20 °C

Target Details for Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Alternative Name: Caspase-7

Background: Caspase-7 (MCH-3, CASP7, ICE LAP 3, CHM-1) along with caspase 3 and 6 form the group of effector caspases that are responsible for the cleavage of multiple substrates including the cytokeratins, PARP, alpha fodrin, NuMA and others. Caspase-7 occurs in three variant forms.

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity