Neurofibromin 1 antibody (AA 27-41)

Catalog No. ABIN187845

This anti-Neurofibromin 1 antibody is a Rabbit Polyclonal antibody detecting Neurofibromin 1 in WB and IF. Suitable for Mammalian.

Quick Overview for Neurofibromin 1 antibody (AA 27-41) (ABIN187845)

Target: Neurofibromin 1 (NF1)

Reactivity: Mammalian

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurofibromin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Neurofibromin 1 Antibody

Binding Specificity: AA 27-41

Specificity: Species Reactivity: Mammals.

Immunogen: Rabbits were immunized with a synthetic peptide based on amino acid residues 27-41 of human neurofibromin.

Application Details

Application Notes: Immunocytochemistry: Use at 1:100 - 1:500 Immunofluorescence: Use at 1:100 - 1:500 Western blot: Use at 1:250 - 1:1,000 The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 200 µl with 50% glycerol and 0.01% thimerosal.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Neurofibromin 1

Target: Neurofibromin 1 (NF1)

Alternative Name: Neurofibromin

Background: Neurofibromin is a tumor suppressor with GTPase activity that modulates the ras pathway. Defects in or deficiency of this protein can lead to neurofibromatosis disease which can result in tumor formation and abnormalities of multiple tissues derived from the embryonic neural crest.

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity