ATP8B3 antibody (N-Term)

Catalog No. ABIN1881094

This Rabbit Polyclonal antibody specifically detects ATP8B3 in WB. It exhibits reactivity toward Human. It has been mentioned in 4+ publications

Quick Overview for ATP8B3 antibody (N-Term) (ABIN1881094)

Target: ATP8B3 (ATPase, Aminophospholipid Transporter, Class I, Type 8B, Member 3 (ATP8B3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP8B3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB42178

Product Details anti-ATP8B3 Antibody

Binding Specificity: AA 56-84, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP8B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human ATP8B3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ATP8B3 antibody (ABIN1881094)

Scott, Muglia, Kong, Guan, Flickinger, Upmanyu, Tozzi, Li, Burmeister, Absher, Thompson, Francks, Meng, Antoniades, Southwick, Schatzberg, Bunney, Barchas, Jones, Day, Matthews, McGuffin et al.: "Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry...." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 18, pp. 7501-6, (2009) (PubMed).

Harris, Arias: "FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body." in: Biochimica et biophysica acta, Vol. 1633, Issue 2, pp. 127-31, (2003) (PubMed).

Halleck, Lawler JF, Blackshaw, Gao, Nagarajan, Hacker, Pyle, Newman, Nakanishi, Ando, Weinstock, Williamson, Schlegel: "Differential expression of putative transbilayer amphipath transporters." in: Physiological genomics, Vol. 1, Issue 3, pp. 139-50, (2000) (PubMed).

Fries, Svendsen: "Studies on Tyzzer's disease in rats." in: Laboratory animals, Vol. 12, Issue 1, pp. 1-4, (1978) (PubMed).

Target Details for ATP8B3

Target: ATP8B3 (ATPase, Aminophospholipid Transporter, Class I, Type 8B, Member 3 (ATP8B3))

Alternative Name: ATP8B3

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. This gene encodes the member 3 of the phospholipid-transporting ATPase 8B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Molecular Weight: 146752

NCBI Accession: NP_001171473, NP_620168

UniProt: O60423