C1GALT1 antibody (AA 115-144)

Catalog No. ABIN1881126

Cited in 3+ publications. The Rabbit Polyclonal anti-C1GALT1 antibody (Clone RB43864) (ABIN1881126) specifically detects C1GALT1 in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for C1GALT1 antibody (AA 115-144) (ABIN1881126)

Target: C1GALT1 (Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 (C1GALT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1GALT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB43864

Product Details anti-C1GALT1 Antibody

Binding Specificity: AA 115-144

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This C1GALT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 amino acids from the Central region of human C1GALT1.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-C1GALT1 antibody (ABIN1881126)

Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).

Ju, Brewer, DSouza, Cummings, Canfield: "Cloning and expression of human core 1 beta1,3-galactosyltransferase." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 178-86, (2002) (PubMed).

Ju, Cummings: "A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16613-8, (2002) (PubMed).

Target Details for C1GALT1

Target: C1GALT1 (Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 (C1GALT1))

Alternative Name: C1GALT1

Background: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.

Molecular Weight: 42203

NCBI Accession: NP_064541

UniProt: Q9NS00