CRYM antibody (AA 154-183)

Catalog No. ABIN1881230

The Rabbit Polyclonal anti-CRYM antibody has been validated for WB. It is suitable to detect CRYM in samples from Mouse. There are 4+ publications available.

Quick Overview for CRYM antibody (AA 154-183) (ABIN1881230)

Target: CRYM (Crystallin, mu (CRYM))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYM antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40546

Product Details anti-CRYM Antibody

Binding Specificity: AA 154-183

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CRYM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the Central region of human CRYM.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CRYM antibody (ABIN1881230)

Al-Kafaji, Malik: "Hyperglycemia induces elevated expression of thyroid hormone binding protein in vivo in kidney and heart and in vitro in mesangial cells." in: Biochemical and biophysical research communications, Vol. 391, Issue 4, pp. 1585-91, (2010) (PubMed).

Malinowska, Cavarretta, Susani, Wrulich, Uberall, Kenner, Culig: "Identification of mu-crystallin as an androgen-regulated gene in human prostate cancer." in: The Prostate, Vol. 69, Issue 10, pp. 1109-18, (2009) (PubMed).

Martins-de-Souza, Gattaz, Schmitt, Maccarrone, Hunyadi-Gulyás, Eberlin, Souza, Marangoni, Novello, Turck, Dias-Neto: "Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia." in: Journal of psychiatric research, Vol. 43, Issue 11, pp. 978-86, (2009) (PubMed).

Martins-de-Souza, Gattaz, Schmitt, Rewerts, Maccarrone, Dias-Neto, Turck: "Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia." in: European archives of psychiatry and clinical neuroscience, Vol. 259, Issue 3, pp. 151-63, (2009) (PubMed).

Target Details for CRYM

Target: CRYM (Crystallin, mu (CRYM))

Alternative Name: CRYM

Background: Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 33776

NCBI Accession: NP_001014444, NP_001879

UniProt: Q14894

Pathways: Hormone Transport, Sensory Perception of Sound