RCAS1 antibody (AA 88-117)

Catalog No. ABIN1881276

Cited in 5+ publications. The Rabbit Polyclonal anti-RCAS1 antibody (Clone RB41813) (ABIN1881276) specifically detects RCAS1 in WB. The antibody is reactive with Human samples.

Quick Overview for RCAS1 antibody (AA 88-117) (ABIN1881276)

Target: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCAS1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41813

Product Details anti-RCAS1 Antibody

Binding Specificity: AA 88-117

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EBAG9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human EBAG9.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-RCAS1 antibody (ABIN1881276)

Wolf, Reimer, Schuck, Rüder, Gerlach, Müller, Otto, Dörken, Rehm: "Role of EBAG9 protein in coat protein complex I-dependent glycoprotein maturation and secretion processes in tumor cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 10, pp. 4000-19, (2010) (PubMed).

Sonoda, Miyamoto, Nakashima, Wake: "Receptor-binding cancer antigen expressed on SiSo cells induces apoptosis via ectodomain shedding." in: Experimental cell research, Vol. 316, Issue 11, pp. 1795-803, (2010) (PubMed).

Ali-Fehmi, Chatterjee, Ionan, Levin, Arabi, Bandyopadhyay, Shah, Bryant, Hewitt, ORand, Alekseev, Morris, Munkarah, Abrams, Tainsky: "Analysis of the expression of human tumor antigens in ovarian cancer tissues." in: Cancer biomarkers : section A of Disease markers, Vol. 6, Issue 1, pp. 33-48, (2010) (PubMed).

Yang, Zhao, Liao, Zhang, Hu, Dai: "[Evaluation of RCAS1 as serum tumor marker for pancreatic cancer]." in: Zhonghua wai ke za zhi [Chinese journal of surgery], Vol. 47, Issue 13, pp. 999-1001, (2009) (PubMed).

Adamek, Radwańska, Gajda: "Expression of RCAS1 protein in microglia/macrophages accompanying brain tumours. An immunofluorescence study." in: Folia neuropathologica, Vol. 47, Issue 3, pp. 240-6, (2009) (PubMed).

Target Details for RCAS1

Target: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Alternative Name: EBAG9

Background: This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.

Molecular Weight: 24377

NCBI Accession: NP_001265867, NP_004206, NP_936056

UniProt: O00559