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EPC1 antibody (AA 305-334)

EPC1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Pubmed (2 references)
Catalog No. ABIN1881300
$429.00
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  • Target See all EPC1 Antibodies
    EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 305-334
    Reactivity
    • 15
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 16
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPC1 antibody is un-conjugated
    Application
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This EPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the Central region of human EPC1.
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, (2004) (PubMed).

    Shimono, Murakami, Hasegawa, Takahashi: "RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions." in: The Journal of biological chemistry, Vol. 275, Issue 50, pp. 39411-9, (2001) (PubMed).

  • Target
    EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))
    Alternative Name
    EPC1 (EPC1 Products)
    Synonyms
    EPC1 antibody, Epl1 antibody, 2400007E14Rik antibody, 5730566F07Rik antibody, A930032N02Rik antibody, epc1 antibody, enhancer of polycomb homolog 1 antibody, enhancer of polycomb homolog 1 (Drosophila) a antibody, enhancer of polycomb homolog 1 (Drosophila) antibody, enhancer of polycomb homolog 1 L homeolog antibody, EPC1 antibody, epc1a antibody, Epc1 antibody, epc1 antibody, epc1.L antibody
    Background
    Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
    Molecular Weight
    93463
    NCBI Accession
    NP_001258933, NP_001258948, NP_001269320, NP_079485
    UniProt
    Q9H2F5
    Pathways
    Regulation of Muscle Cell Differentiation
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