GEMIN4 antibody (N-Term)

Catalog No. ABIN1881369

Cited in 4+ publications. The Rabbit Polyclonal anti-GEMIN4 antibody (Clone RB41821) (ABIN1881369) specifically detects GEMIN4 in WB. The antibody is reactive with Human samples.

Quick Overview for GEMIN4 antibody (N-Term) (ABIN1881369)

Target: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEMIN4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41821

Product Details anti-GEMIN4 Antibody

Binding Specificity: AA 273-301, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GEMIN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the N-terminal region of human GEMIN4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GEMIN4 antibody (ABIN1881369)

Clague, Lippman, Yang, Hildebrandt, Ye, Lee, Wu: "Genetic variation in MicroRNA genes and risk of oral premalignant lesions." in: Molecular carcinogenesis, Vol. 49, Issue 2, pp. 183-9, (2010) (PubMed).

Kim, Choi, Jin, Kang, Choi, Jeon, Lee, Kim, Kim, Kim, Son, Jung, Park: "Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study." in: Molecular carcinogenesis, Vol. 49, Issue 10, pp. 913-21, (2010) (PubMed).

Wilker, Baccarelli, Suh, Vokonas, Wright, Schwartz: "Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in MicroRNA processing genes." in: Environmental health perspectives, Vol. 118, Issue 7, pp. 943-8, (2010) (PubMed).

Ye, Wang, Gu, Yang, Lin, Ajani, Wu: "Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk." in: Cancer prevention research (Philadelphia, Pa.), Vol. 1, Issue 6, pp. 460-9, (2009) (PubMed).

Target Details for GEMIN4

Target: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Alternative Name: GEMIN4

Background: The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Molecular Weight: 120037

NCBI Accession: NP_056536

UniProt: P57678

Pathways: Ribonucleoprotein Complex Subunit Organization