GGT1 antibody (N-Term)

Catalog No. ABIN1881372

Cited in 3+ publications. The Rabbit Polyclonal anti-GGT1 antibody (Clone RB40721) (ABIN1881372) specifically detects GGT1 in WB. The antibody is reactive with Mouse and Rat samples.

Quick Overview for GGT1 antibody (N-Term) (ABIN1881372)

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGT1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40721

Product Details anti-GGT1 Antibody

Binding Specificity: AA 12-39, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Rat Ggt1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of rat Ggt1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GGT1 antibody (ABIN1881372)

Aly, Lightfoot, El-Shemy: "Modulatory role of lipoic acid on lipopolysaccharide-induced oxidative stress in adult rat Sertoli cells in vitro." in: Chemico-biological interactions, Vol. 182, Issue 2-3, pp. 112-8, (2009) (PubMed).

Hamden, Carreau, Ellouz, Masmoudi, El: "Protective effect of 17beta-estradiol on oxidative stress and liver dysfunction in aged male rats." in: Journal of physiology and biochemistry, Vol. 63, Issue 3, pp. 195-201, (2008) (PubMed).

Pandur, Pankiv, Johannessen, Moens, Huseby: "Gamma-glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells." in: Free radical research, Vol. 41, Issue 12, pp. 1376-84, (2007) (PubMed).

Target Details for GGT1

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Alternative Name: Ggt1

Background: Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate.

Molecular Weight: 61610

NCBI Accession: NP_446292

UniProt: P07314