Lrig1 antibody (C-Term)
Quick Overview for Lrig1 antibody (C-Term) (ABIN1881506)
Target
See all Lrig1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 801-829, C-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This LRIG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 801-829 amino acids from the C-terminal region of human LRIG1.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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: "Upregulation of LRIG1 suppresses malignant glioma cell growth by attenuating EGFR activity." in: Journal of neuro-oncology, Vol. 94, Issue 2, pp. 183-94, (2009) (PubMed).
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- Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))
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Alternative Name
- LRIG1
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Background
- LRIG1 act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
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Molecular Weight
- 119113
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NCBI Accession
- NP_056356
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UniProt
- Q96JA1
Target
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