PFDN2 antibody (C-Term)

Catalog No. ABIN1881647

Product Details anti-PFDN2 Antibody

Target: PFDN2 (Prefoldin Subunit 2 (PFDN2))

Binding Specificity: AA 97-125, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFDN2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PFDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-125 amino acids from the C-terminal region of human PFDN2.

Clone: RB39208

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PFDN2 antibody (ABIN1881647)

Cloutier, Al-Khoury, Lavallée-Adam, Faubert, Jiang, Poitras, Bouchard, Forget, Blanchette, Coulombe: "High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes." in: Methods (San Diego, Calif.), Vol. 48, Issue 4, pp. 381-6, (2009) (PubMed).

Bouwmeester, Bauch, Ruffner, Angrand, Bergamini, Croughton, Cruciat, Eberhard, Gagneur, Ghidelli, Hopf, Huhse, Mangano, Michon, Schirle, Schlegl, Schwab, Stein, Bauer, Casari, Drewes, Gavin, Jackson et al.: "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ..." in: Nature cell biology, Vol. 6, Issue 2, pp. 97-105, (2004) (PubMed).

Target Details for PFDN2

Target: PFDN2 (Prefoldin Subunit 2 (PFDN2))

Alternative Name: PFDN2 (PFDN2 Products)

Background: This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.

Molecular Weight: 16648

NCBI Accession: NP_036526

UniProt: Q9UHV9

Pathways: Unfolded Protein Response