RBCK1 antibody (N-Term)

Catalog No. ABIN1881731

There are 3+ publications for this product available. The Rabbit Polyclonal anti-RBCK1 antibody is suitable to detect RBCK1 in samples from Human. It has been validated for WB.

Quick Overview for RBCK1 antibody (N-Term) (ABIN1881731)

Target: RBCK1 (RanBP-Type and C3HC4-Type Zinc Finger Containing 1 (RBCK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBCK1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB42651

Product Details anti-RBCK1 Antibody

Binding Specificity: AA 1-30, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RBCK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RBCK1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-RBCK1 antibody (ABIN1881731)

Gustafsson, Zhao, Gustafsson, Dahlman-Wright: "RBCK1 drives breast cancer cell proliferation by promoting transcription of estrogen receptor alpha and cyclin B1." in: Cancer research, Vol. 70, Issue 3, pp. 1265-74, (2010) (PubMed).

Yoshimoto, Tatematsu, Okajima, Tanizawa, Kuroda: "Accumulation of polyubiquitinated proteins by overexpression of RBCC protein interacting with protein kinase C2, a splice variant of ubiquitin ligase RBCC protein interacting with protein kinase C1." in: The FEBS journal, Vol. 276, Issue 21, pp. 6375-85, (2009) (PubMed).

Tokunaga, Sakata, Saeki, Satomi, Kirisako, Kamei, Nakagawa, Kato, Murata, Yamaoka, Yamamoto, Akira, Takao, Tanaka, Iwai: "Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation." in: Nature cell biology, Vol. 11, Issue 2, pp. 123-32, (2009) (PubMed).

Target Details for RBCK1

Target: RBCK1 (RanBP-Type and C3HC4-Type Zinc Finger Containing 1 (RBCK1))

Alternative Name: RBCK1

Background: The protein encoded by this gene is similar to mouse UIP28/UbcM4 interacting protein. Alternative splicing has been observed at this locus, resulting in distinct isoforms. [provided by RefSeq].

Molecular Weight: 57572

NCBI Accession: NP_006453, NP_112506

UniProt: Q9BYM8