RBPMS antibody (C-Term)

Catalog No. ABIN1881736

This Rabbit Polyclonal antibody specifically detects RBPMS in WB. It exhibits reactivity toward Human.

Quick Overview for RBPMS antibody (C-Term) (ABIN1881736)

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBPMS antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB42810

Product Details anti-RBPMS Antibody

Binding Specificity: AA 166-193, C-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RBPMS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from the C-terminal region of human RBPMS.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for RBPMS

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Alternative Name: RBPMS

Background: Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.

Molecular Weight: 21802

NCBI Accession: NP_001008710, NP_001008711, NP_001008712, NP_006858

UniProt: Q93062