SERPINB8 antibody (C-Term)

Catalog No. ABIN1881791

Product Details anti-SERPINB8 Antibody

Target: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Binding Specificity: AA 274-301, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINB8 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SERPINB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-301 amino acids from the C-terminal region of human SERPINB8.

Clone: RB42352

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SERPINB8

Target: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Alternative Name: SERPINB8 (SERPINB8 Products)

Synonyms: pi8 antibody, cap2 antibody, CAP-2 antibody, CAP2 antibody, NK10 antibody, Spi8 antibody, ovalbumin antibody, PI8 antibody, serpin family B member 8 antibody, serpin B8 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 8 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 8 antibody, Serpinb8 antibody, SERPINB8 antibody, LOC607205 antibody, serpinb8 antibody, LOC100424017 antibody

Background: The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8, SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).

Molecular Weight: 42767

NCBI Accession: NP_001027018, NP_001263419, NP_002631, NP_942130

UniProt: P50452