SHC4 antibody (C-Term)

Catalog No. ABIN1881806

There are 2+ publications for this product available. The Rabbit Polyclonal anti-SHC4 antibody is suitable to detect SHC4 in samples from Mouse. It has been validated for WB.

Quick Overview for SHC4 antibody (C-Term) (ABIN1881806)

Target: SHC4 (SHC (Src Homology 2 Domain Containing) Family, Member 4 (SHC4))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHC4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40853

Product Details anti-SHC4 Antibody

Binding Specificity: AA 590-617, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Shc4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 590-617 amino acids from the C-terminal region of mouse Shc4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-SHC4 antibody (ABIN1881806)

Jones, Hardy, Friese, Jorgensen, Smith, Woody, Burden, Pawson: "Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase." in: Molecular and cellular biology, Vol. 27, Issue 13, pp. 4759-73, (2007) (PubMed).

Fagiani, Giardina, Luzi, Cesaroni, Quarto, Capra, Germano, Bono, Capillo, Pelicci, Lanfrancone: "RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas." in: Cancer research, Vol. 67, Issue 7, pp. 3064-73, (2007) (PubMed).

Target Details for SHC4

Target: SHC4 (SHC (Src Homology 2 Domain Containing) Family, Member 4 (SHC4))

Alternative Name: Shc4

Background: Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.

Molecular Weight: 68519

NCBI Accession: NP_950187

UniProt: Q6S5L9