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SIKE1 antibody (N-Term)

SIKE1 Reactivity: Mouse WB Host: Rabbit Polyclonal RB42417 unconjugated
Catalog No. ABIN1881808
  • Target See all SIKE1 Antibodies
    SIKE1 (Suppressor of IKBKE 1 (SIKE1))
    Binding Specificity
    • 13
    • 9
    • 8
    • 7
    • 6
    AA 36-63, N-Term
    Reactivity
    • 19
    • 17
    • 2
    Mouse
    Host
    • 32
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 12
    • 4
    • 4
    • 4
    • 4
    • 4
    This SIKE1 antibody is un-conjugated
    Application
    • 32
    • 26
    • 14
    • 2
    Western Blotting (WB)
    Predicted Reactivity
    Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.
    Clone
    RB42417
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SIKE1 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Katayama, Tomaru, Kasukawa, Waki, Nakanishi, Nakamura, Nishida, Yap, Suzuki, Kawai, Suzuki, Carninci, Hayashizaki, Wells, Frith, Ravasi, Pang, Hallinan, Mattick, Hume, Lipovich, Batalov et al.: "Antisense transcription in the mammalian transcriptome...." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1564-6, (2005) (PubMed).

  • Target
    SIKE1 (Suppressor of IKBKE 1 (SIKE1))
    Alternative Name
    Sike1 (SIKE1 Products)
    Synonyms
    SIKE antibody, 2810005O12Rik antibody, 5730470L24Rik antibody, AI450236 antibody, AI839862 antibody, Sike antibody, Sikeb antibody, RGD1311316 antibody, suppressor of IKBKE 1 antibody, SIKE1 antibody, Sike1 antibody
    Background
    Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).
    Molecular Weight
    23522
    NCBI Accession
    NP_079955
    UniProt
    Q9CPR7
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