TAF11 antibody (N-Term)

Catalog No. ABIN1881867

Cited in 5+ publications. The Rabbit Polyclonal anti-TAF11 antibody (Clone RB41941) (ABIN1881867) specifically detects TAF11 in WB. The antibody is reactive with Human samples.

Quick Overview for TAF11 antibody (N-Term) (ABIN1881867)

Target: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF11 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41941

Product Details anti-TAF11 Antibody

Binding Specificity: AA 1-30, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TAF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TAF11.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-TAF11 antibody (ABIN1881867)

Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, (2007) (PubMed).

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

Guermah, Ge, Chiang, Roeder: "The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis." in: Molecular cell, Vol. 12, Issue 4, pp. 991-1001, (2003) (PubMed).

Mengus, Gangloff, Carré, Lavigne, Davidson: "The human transcription factor IID subunit human TATA-binding protein-associated factor 28 interacts in a ligand-reversible manner with the vitamin D(3) and thyroid hormone receptors." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10064-71, (2000) (PubMed).

Birck, Poch, Romier, Ruff, Mengus, Lavigne, Davidson, Moras: "Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family." in: Cell, Vol. 94, Issue 2, pp. 239-49, (1998) (PubMed).

Target Details for TAF11

Target: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Alternative Name: TAF11

Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.

Molecular Weight: 23307

NCBI Accession: NP_001257417, NP_005634

UniProt: Q15544