TH antibody (C-Term)

Catalog No. ABIN1881881

The Rabbit Polyclonal anti-TH antibody has been validated for WB, FACS and IHC (p). It is suitable to detect TH in samples from Human. There is 1 publication available.

Quick Overview for TH antibody (C-Term) (ABIN1881881)

Target: TH

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TH antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB21096

Product Details anti-TH Antibody

Binding Specificity: AA 486-514, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Immunogen: This TH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 486-514 amino acids from the C-terminal region of human TH.

Application Details

Application Notes: WB: 1:1000,IHC (p): 1:50-100,FACS: 1:10-50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-TH antibody (ABIN1881881)

Kuhn, Sadidi, Liu, Kreipke, Geddes, Borges, Watson et al.: "Peroxynitrite-induced nitration of tyrosine hydroxylase: identification of tyrosines 423, 428, and 432 as sites of modification by matrix-assisted laser desorption ionization time-of-flight mass..." in: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 14336-42, (2002) (PubMed).

Target Details for TH

Target: TH

Background: TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons.

Synonyms: TH, TYH, Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase

NCBI Accession: NP_954986, NP_954987, NP_000351

UniProt: P07101