TH antibody (N-Term)

Catalog No. ABIN2792118

This Rabbit Polyclonal antibody specifically detects TH in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Zebrafish (Danio rerio), Rabbit and Cow.

Quick Overview for TH antibody (N-Term) (ABIN2792118)

Target: TH

Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TH Antibody

Binding Specificity: N-Term

Purpose: TH Antibody - N-terminal region

Sequence: MPTPDATTPQ AKGFRRAVSE LDAKQAEAIM VRGQSPRFIG RRQSLIEDAR

Predicted Reactivity: Cow: 90%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human TH

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TH

Target: TH

Background:

Background Information: Plays an important role in the physiology of adrenergic neurons. Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons.

Gene Name: Tyrosine hydroxylase

Alternative Symbols: TYH, DYT14, DYT5b

Protein Name: Tyrosine 3-monooxygenase Ensembl ENSP00000328814

Molecular Weight: 45kDa

Gene ID: 7054

UniProt: Q0PWM2