TIMD4 antibody (C-Term)

Catalog No. ABIN1881886

This Rabbit Polyclonal antibody specifically detects TIMD4 in WB. It exhibits reactivity toward Human. It has been mentioned in 5+ publications

Quick Overview for TIMD4 antibody (C-Term) (ABIN1881886)

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMD4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40431

Product Details anti-TIMD4 Antibody

Binding Specificity: AA 333-361, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TIMD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-361 amino acids from the C-terminal region of human TIMD4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-TIMD4 antibody (ABIN1881886)

Dorfman, Hornick, Shahsafaei, Freeman: "The phosphatidylserine receptors, T cell immunoglobulin mucin proteins 3 and 4, are markers of histiocytic sarcoma and other histiocytic and dendritic cell neoplasms." in: Human pathology, Vol. 41, Issue 10, pp. 1486-94, (2010) (PubMed).

Zhao, Xu, Wang, Liang, Qi, Liu, Guo, Zhang, Ma, Gao: "Increased expression of human T-cell immunoglobulin- and mucin-domain-containing molecule-4 in peripheral blood mononuclear cells from patients with system lupus erythematosus." in: Cellular & molecular immunology, Vol. 7, Issue 2, pp. 152-6, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Cai, Hu, Cui, Li, Chen, Wu: "Association of TIM4 promoter polymorphism -1419G>A with childhood asthma in a Chinese Han population." in: Tissue antigens, Vol. 74, Issue 1, pp. 11-6, (2009) (PubMed).

Park, Hochreiter-Hufford, Ravichandran: "The phosphatidylserine receptor TIM-4 does not mediate direct signaling." in: Current biology : CB, Vol. 19, Issue 4, pp. 346-51, (2009) (PubMed).

Target Details for TIMD4

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Alternative Name: TIMD4

Background: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1 (By similarity).

Molecular Weight: 41578

NCBI Accession: NP_001140198, NP_612388

UniProt: Q96H15

Pathways: Cancer Immune Checkpoints