TMPRSS6 antibody (N-Term)

Catalog No. ABIN1881891

Cited in 2+ publications. The Rabbit Polyclonal anti-TMPRSS6 antibody (Clone RB39227) (ABIN1881891) specifically detects TMPRSS6 in WB. The antibody is reactive with Human samples.

Quick Overview for TMPRSS6 antibody (N-Term) (ABIN1881891)

Target: TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS6 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB39227

Product Details anti-TMPRSS6 Antibody

Binding Specificity: AA 85-114, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TMPRSS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the N-terminal region of human TMPRSS6.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-TMPRSS6 antibody (ABIN1881891)

Altamura, DAlessio, Selle, Muckenthaler: "A novel TMPRSS6 mutation that prevents protease auto-activation causes IRIDA." in: The Biochemical journal, Vol. 431, Issue 3, pp. 363-71, (2010) (PubMed).

Ucisik-Akkaya, Davis, Do, Morrison, Stemmer, Amadio, Dorak: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).

Target Details for TMPRSS6

Target: TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))

Alternative Name: TMPRSS6

Background: The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.

Molecular Weight: 90000

NCBI Accession: NP_705837

UniProt: Q8IU80

Pathways: Transition Metal Ion Homeostasis