TTBK1 antibody (AA 667-695)

Catalog No. ABIN1881954

Cited in 2+ publications. The Rabbit Polyclonal anti-TTBK1 antibody (Clone RB42064) (ABIN1881954) specifically detects TTBK1 in WB. The antibody is reactive with Human samples.

Quick Overview for TTBK1 antibody (AA 667-695) (ABIN1881954)

Target: TTBK1 (tau Tubulin Kinase 1 (TTBK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTBK1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB42064

Product Details anti-TTBK1 Antibody

Binding Specificity: AA 667-695

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TTBK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 667-695 amino acids from the Central region of human TTBK1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-TTBK1 antibody (ABIN1881954)

Sato, Xu, Okuyama, Martinez, Walsh, Jacobsen, Swan, Schlautman, Ciborowski, Ikezu: "Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 53, pp. 14511-21, (2009) (PubMed).

Takahashi, Tomizawa, Sato, Ohtake, Omori: "A novel tau-tubulin kinase from bovine brain." in: FEBS letters, Vol. 372, Issue 1, pp. 59-64, (1995) (PubMed).

Target Details for TTBK1

Target: TTBK1 (tau Tubulin Kinase 1 (TTBK1))

Alternative Name: TTBK1

Background: Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.

Molecular Weight: 142737

NCBI Accession: NP_115927

UniProt: Q5TCY1