ULK2 antibody (pSer323)

Catalog No. ABIN1881982

This Rabbit Polyclonal antibody specifically detects ULK2 in DB. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for ULK2 antibody (pSer323) (ABIN1881982)

Target: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULK2 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: RB40763

Product Details anti-ULK2 Antibody

Binding Specificity: pSer323

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ULK2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S323 of human ULK2.

Isotype: Ig Fraction

Application Details

Application Notes: DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ULK2 antibody (ABIN1881982)

Jung, Jun, Ro, Kim, Otto, Cao, Kundu, Kim: "ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1992-2003, (2009) (PubMed).

Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).

Yan, Kuroyanagi, Tomemori, Okazaki, Asato, Matsuda, Suzuki, Ohshima, Mitani, Masuho, Shirasawa, Muramatsu: "Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains." in: Oncogene, Vol. 18, Issue 43, pp. 5850-9, (1999) (PubMed).

Target Details for ULK2

Target: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Alternative Name: ULK2

Background: This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq].

Molecular Weight: 112694

NCBI Accession: NP_001136082, NP_055498

UniProt: Q8IYT8

Pathways: Regulation of Cell Size, Autophagy