VAPA antibody (C-Term)

Catalog No. ABIN1881990

Cited in 5+ publications. The Rabbit Polyclonal anti-VAPA antibody (Clone RB40543) (ABIN1881990) specifically detects VAPA in WB. The antibody is reactive with Human samples.

Quick Overview for VAPA antibody (C-Term) (ABIN1881990)

Target: VAPA (VAMP (Vesicle-Associated Membrane Protein)-Associated Protein A, 33kDa (VAPA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAPA antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40543

Product Details anti-VAPA Antibody

Binding Specificity: AA 182-210, C-Term

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This VAPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-210 amino acids from the C-terminal region of human VAPA.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-VAPA antibody (ABIN1881990)

Furuita, Jee, Fukada, Mishima, Kojima: "Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies." in: The Journal of biological chemistry, Vol. 285, Issue 17, pp. 12961-70, (2010) (PubMed).

Tuuf, Wistbacka, Mattjus: "The glycolipid transfer protein interacts with the vesicle-associated membrane protein-associated protein VAP-A." in: Biochemical and biophysical research communications, Vol. 388, Issue 2, pp. 395-9, (2009) (PubMed).

Saita, Shirane, Natume, Iemura, Nakayama: "Promotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated protein." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13766-77, (2009) (PubMed).

Prosser, Tran, Gougeon, Verly, Ngsee: "FFAT rescues VAPA-mediated inhibition of ER-to-Golgi transport and VAPB-mediated ER aggregation." in: Journal of cell science, Vol. 121, Issue Pt 18, pp. 3052-61, (2008) (PubMed).

Lohoff, Weller, Bloch, Nall, Ferraro, Berrettini: "Association between polymorphisms in the vesicle-associated membrane protein-associated protein A (VAPA) gene on chromosome 18p and bipolar disorder." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 115, Issue 9, pp. 1339-45, (2008) (PubMed).

Target Details for VAPA

Target: VAPA (VAMP (Vesicle-Associated Membrane Protein)-Associated Protein A, 33kDa (VAPA))

Alternative Name: VAPA

Background: The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Molecular Weight: 27893

NCBI Accession: NP_003565, NP_919415

UniProt: Q9P0L0