Zinc Finger Protein 185 antibody (N-Term)

Catalog No. ABIN1882016

Product Details anti-Zinc Finger Protein 185 Antibody

Target: Zinc Finger Protein 185 (ZNF185)

Binding Specificity: AA 155-183, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Zinc Finger Protein 185 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZNF185 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the N-terminal region of human ZNF185.

Clone: RB41581

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Zinc Finger Protein 185 antibody (ABIN1882016)

Zhang, Gong, Young: "ZNF185, an actin-cytoskeleton-associated growth inhibitory LIM protein in prostate cancer." in: Oncogene, Vol. 26, Issue 1, pp. 111-22, (2007) (PubMed).

Medina, Carretero, Ballestar, Angulo, Lopez-Rios, Esteller, Sanchez-Cespedes: "Transcriptional targets of the chromatin-remodelling factor SMARCA4/BRG1 in lung cancer cells." in: Human molecular genetics, Vol. 14, Issue 7, pp. 973-82, (2005) (PubMed).

Vanaja, Cheville, Iturria, Young: "Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression." in: Cancer research, Vol. 63, Issue 14, pp. 3877-82, (2003) (PubMed).

Mallon, Platzer, Bate, Gloeckner, Botcherby, Nordsiek, Strivens, Kioschis, Dangel, Cunningham, Straw, Weston, Gilbert, Fernando, Goodall, Hunter, Greystrong, Clarke, Kimberley, Goerdes, Blechschmidt et al.: "Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. ..." in: Genome research, Vol. 10, Issue 6, pp. 758-75, (2000) (PubMed).

Heiss, Gloeckner, Bächner, Kioschis, Klauck, Hinzmann, Rosenthal, Herman, Poustka: "Genomic structure of a novel LIM domain gene (ZNF185) in Xq28 and comparisons with the orthologous murine transcript." in: Genomics, Vol. 43, Issue 3, pp. 329-38, (1997) (PubMed).

Target Details for Zinc Finger Protein 185

Target: Zinc Finger Protein 185 (ZNF185)

Alternative Name: ZNF185 (ZNF185 Products)

Synonyms: P1 antibody, Znf185 antibody, zinc finger protein 185 with LIM domain antibody, zinc finger protein 185 antibody, ZNF185 antibody, LOC693882 antibody, Zfp185 antibody

Background: Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

NCBI Accession: NP_001171577, NP_001171578, NP_001171579, NP_001171580, NP_001171581, NP_001171584, NP_009081

UniProt: O15231